hrp0095p1-291 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2022

Bronchopulmonary dysplasia is not related to neurofilament light chain for neuroaxonal damage in preterm infants

Romijn Michelle , Baas Emma , Lissenberg-Witte Birgit , Onland Wes , Königs Marsh , Oosterlaan Jaap , Heijst Hans , Rotteveel Joost , van Kaam Anton , Teunissen Charlotte , Finken Martijn

Rationale: Bronchopulmonary dysplasia (BPD) is a common complication after preterm birth that is associated with neurodevelopmental impairment. Neurofilament light chain (NfL) has been identified as a biomarker for neuroaxonal damage in preterm infants, but its relation with BPD has not yet been established. We hypothesized that BPD is associated with increased NfL levels at an early stage, indicative of early neuroaxonal damage....